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Professor Silvia Giordani, Chair of Nano materials at Dublin City University, is developing bio-inspired carbon-based nanoplatforms to deliver cancer drugs more precisely. With her team at DCU’s School of Chemical Sciences, Prof Giordani describes the potential of nanotechnology to transform the fight against aggressive cancers like glioblastoma, breast and pancreatic cancer whilst reducing side effects, and improve treatment outcomes.

Il metodo di somministrazione del farmaco basato sulla nanotecnologia utilizzato e sviluppato da Giordani consente, infatti, di somministrare una maggiore quantità di farmaco direttamente al ‘bersaglio’, con minori danni collaterali alle cellule sane circostanti.

Nanotechnology drug delivery could mean faster treatments and reduced hair loss, nausea and fatigue

Cancer is one of the leading causes of death worldwide and represents a significant burden on global health systems. Many existing chemotherapy treatments come with severe side effects, ranging from hair loss to cardiotoxicity and many types of cancer express chemotherapy resistance such as triple-negative breast cancer. This study presents a novel boron/nitrogen-doped carbon nano-onion (BN-CNO) …

Hugh Mohan, a final-year PhD student in the Giordani Group, delivered an exceptional presentation at the DCU Tell It Straight Final on March 5th and earned the Runner-Up Prize. His PhD research focuses on using boron and nitrogen-doped carbon nano-onions as nanocarriers to enhance breast cancer therapy.

Carbon dots (CDs) are small-sized, spherical nanoparticles presenting amorphous carbon cores with nanocrystalline regions of a graphitic structure. They show unique properties such as high aqueous solubility, robust chemical inertness, and non-toxicity and can be manufactured at a relatively low cost. They are also well known for outstanding fluorescence tunability and resistance to …